In most plants and animals, including humans, mitochondria are inherited exclusively, or nearly exclusively, from the mother.

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

A new study shows that plants can inherit mitochondria from their father, restoring fertility when maternal mitochondria are defective, challenging traditional views on mitochondrial inheritance.

In a step toward treating mitochondrial diseases, researchers at the University Medical Center Utrecht and their colleagues have used mitochondrial base editing (mtBE) to successfully edit harmful ...

Mitochondrial DNA heteroplasmy is independently associated with an increased risk of CLL, suggesting potential as a novel biomarker for early risk identification.

Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might ...

New molecule halts mitochondrial DNA loss before it triggers inflammation. When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration and ...

David Rand, a professor of natural history at Brown University, explains how studying mitochondria — the cell's energy producers — offers a useful way to understand complex gene-by-gene or ...

Many mitochondrial diseases have been difficult to study and treat due to the inherent challenges in accessing mitochondrial DNA (mtDNA). Now, researchers have optimized mitochondrial-targeted ...

New evidence from Indian patients shows that severe COVID-19 is associated with distinct mitochondrial methylation signatures and altered mitochondrial proteins, pointing to disrupted energy ...

Researchers uncover how cells internalize transplanted mitochondria, paving the way for new energy-restoring therapies for Parkinson’s and Alzheimer’s.