Calcium channel blockers are a common cause of poisoning and are associated with high mortality in affected patients.

A team of researchers has found that mutations in the calcium channel protein RyR1 that confer susceptibility to malignant hyperthermia make the protein hypersensitive to heat, which triggers ...

Imbibing calcium in supplement form may be associated with an increased risk of plaque buildup in the arteries and heart damage, according to a recent study published in the Journal of the American ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Praxis Precision Medicines' ulixacaltamide (PRAX-944) is a potent and selective small molecule T-type Ca2+ channel blocker being developed for the potential treatment of essential tremor. ET is a ...

When you have atrial fibrillation, the two upper chambers of your heart (atria) don't beat in sync with the two lower chambers (ventricles). This makes your heart beat out of rhythm and sometimes very ...

A systematic review evaluated the efficacy of calcium channel blockers or alpha blockers for the treatment of urinary stones in nine randomized trials with 693 patients (Lancet. 2006;368:1171-1179).

Myotonic dystrophy is one of the most common forms of muscular dystrophy. It is a genetic condition that causes progressive muscle weakness and wasting. No treatments currently exist that slow the ...

Evidence from randomized trials suggests that calcium supplements may not significantly reduce fracture risk in ...