The current path to CAR-T cell therapy is, by any measure, a logistical ordeal. A patient’s immune cells must be drawn out of the body, shipped to a specialized facility, genetically reprogrammed, ...

A new study reveals how the brain triggers the breakdown of stable fat cells that normally resist diet and exercise. This ...

UCSF scientists found a precise way to turn on cancer-fighting immune cells inside the body. This more potent form of CAR-T ...

Each year, the world bids adieu to roughly 60 million individuals. Death, a universal yet often misunderstood happening, inspires a combination of fear, fascination, and deep curiosity. It’s a ...

For decades, lab-grown cells have been studied in materials that don't reflect the softness and flexibility of human tissue.

The GPR133 receptor is expressed by osteoblasts, the cells that make bone. The study suggests that this receptor helps those cells sense two kinds of input: mechanical strain and signals relayed by ...

Every multicellular organism, from tiny worms to humans, elephants, and whales, needs a way for their cells to connect with each other to form tissues, organs, and organize their overall body plan.

The massive reptile may have weighed more than 4.5 tons and been 35 feet long—much bigger than its related peers at the time ...

Bonnie was exhausted. It was late 2001, and she’d been working a high-pressure job – barely getting any sleep. “I’d wake up tired, I’d go to bed tired,” she says. She didn’t think much of it, but she ...

When a patient is diagnosed with osteosarcoma, an aggressive form of bone cancer, the mission is to remove the tumor entirely. Leaving behind even a microscopic cluster of malignant cells can be the ...

The human body can do remarkable things, repairing bone fractures through a complex healing process that gradually rebuilds bone.

A Central Square woman is turning one of her hardest battles of her life into a message of hope for others after being ...