Abstract: Enzyme function classification plays a critical role in understanding biological processes, drug discovery, and protein annotation. This paper presents a computational pipeline that ...

The use of chemical insecticides continues to play a major role in the control of disease vector populations, which is leading to the global dissemination of insecticide resistance. A greater capacity ...

Scientists discovered that alcohol activates a sugar-producing pathway in the body, creating fructose that may reinforce addictive drinking. The enzyme responsible, KHK, appears to drive both alcohol ...

So, what type of molecule is an enzyme? While the vast majority of enzymes are proteins, a small but important group, known as ribozymes, is made of RNA. Proteins are large molecules built from long ...

Pull requests help you collaborate on code with other people. As pull requests are created, they’ll appear here in a searchable and filterable list. To get started, you should create a pull request.

In a new paper, scientists have reported the first successful human transplant of a kidney converted from blood type A to the universal type O using special enzymes developed at the University of ...

Enzymes are proteins that guide (catalyze) very specific chemical reactions. They play indispensable roles in all life forms. Some enzymes carry out the day-to-day business of biology like digesting ...

The est2 gene was cloned into the pMAL-c2x vector containing an MBP-tag The MBP tag was used because it enhances the solubility of the recombinant protein (~40 kDa) and facilitates subsequent ...

Researchers have developed a new workflow for designing enzymes from scratch, paving the way toward more efficient, powerful and environmentally benign chemistry. The new method allows designers to ...

A new method that successfully designs serine hydrolase enzymes capable of catalyzing ester hydrolysis with high efficiency, demonstrates a computational approach for creating de novo enzymes that ...