Researchers at Karolinska Institutet have created the first detailed map showing how genetic activity is controlled in individual cells of the adult human brain and spinal cord. The study, published ...

The current path to CAR-T cell therapy is, by any measure, a logistical ordeal. A patient’s immune cells must be drawn out of the body, shipped to a specialized facility, genetically reprogrammed, ...

The researchers say that, to their knowledge, this is the first demonstration of programmable, site-specific integration of a large DNA payload into T cells in vivo.

A new study reveals how the brain triggers the breakdown of stable fat cells that normally resist diet and exercise. This ...

UCSF scientists found a precise way to turn on cancer-fighting immune cells inside the body. This more potent form of CAR-T ...

Researchers show that pharmacological activation of hypoxia signaling improves metabolism, limits fat accumulation, and ...

Study finds childhood PFAS exposure, especially PFOA, linked to lower adolescent bone mineral density and possible higher ...

Each year, the world bids adieu to roughly 60 million individuals. Death, a universal yet often misunderstood happening, inspires a combination of fear, fascination, and deep curiosity. It’s a ...

For decades, lab-grown cells have been studied in materials that don't reflect the softness and flexibility of human tissue.

The GPR133 receptor is expressed by osteoblasts, the cells that make bone. The study suggests that this receptor helps those cells sense two kinds of input: mechanical strain and signals relayed by ...

Every multicellular organism, from tiny worms to humans, elephants, and whales, needs a way for their cells to connect with each other to form tissues, organs, and organize their overall body plan.