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You started HRT thinking it would finally help you lose that stubborn belly fat, but for some people, the opposite happens. Here’s what most don’t realize: extra estrogen can change how your thyroid works. It can make it harder for your body to convert T4 into the active thyroid hormone T3, the one that actually keeps your metabolism humming. Progesterone and testosterone help with that conversion, so if those are low or out of balance, your body might be working against your fat-loss goals, not
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Started HRT and felt worse? It’s not in your head. It may actually be a histamine issue. 1. Estrogen makes mast cells unstable. It triggers histamine release, blocks your ability to break it down, and ramps up histamine receptors. 2. Histamine drives more estrogen production. It stimulates your brain to pump out GnRH and LH, pushing your ovaries to make more estrogen. Cue the loop of anxiety, inflammation, and overload. 3. It’s not always estradiol, it may be estrone. Estrone is the sneaky, pro-
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